在有或没有宫内生长限制的早产新生儿中,骨状况和早期营养
Marta Meneghelli1, Andrea Peruzzo1, Elena Priante1
1Neonatal Intensive Care Unit, Department of Women's and Children's Health, University Hospital of Padova, 35128 Padova, Italy.
Nutrients
|November 25, 2023
概括
宫内生长限制 (IUGR) 和早产会对骨健康产生负面影响. 最佳的营养管理,包括足够的能量和维生素D,对于改善这些脆弱新生儿的骨状况至关重要.
科学领域:
- 新生儿科学 新生儿科学
- 儿童骨健康 儿童骨健康
- 营养科学 营养科学
背景情况:
- 宫内生长限制 (IUGR) 与早产相结合,对婴儿骨发育构成重大风险.
- 评估早产婴儿的骨质状况,特别是那些患有IUGR的婴儿,对于早期干预至关重要.
- 营养管理在早产新生儿的骨健康中起着关键作用.
研究的目的:
- 为了比较早产婴儿与没有IUGR之间的骨质状况.
- 确定与IUGR早产婴儿骨质状况改善相关的营养管理策略.
- 分析影响早产新生儿到36周妊娠年龄骨发育的因素.
主要方法:
- 监测了一组150名早产新生儿 (<34周妊娠年龄),包括75名IUGR和75名非IUGR婴儿.
- 骨状况通过量化超声波评估,使用骨骨传输时间 (mc-BTT) 来评估.
- 人类测量测量,生物化学参数 (酸盐) 和营养摄入量 (腹腔营养) 被跟踪.
主要成果:
- 与非IUGR婴儿相比,IUGR婴儿在出生时表现出明显较低的平均mc-BTT和血酸盐水平.
- 在36周妊娠时代,mc-BTT与初始酸盐,能量摄入量正相关,与IUGR婴儿完全肠道食的时间负相关.
- 较低的静脉注射维生素D,较低的下肢长度 (LLL) 和长时间的全肠直肠营养预测了36周的较差的mc-BTT.
结论:
- 过早出生的婴儿,特别是那些患有IUGR的婴儿,在出生时表现出受损的骨状况.
- 具体的营养干预措施,包括足够的能量,和维生素D,对于这些婴儿的骨发育至关重要.
- 需要仔细监测和量身定制的营养策略,以优化IUGR早产新生儿的骨健康结果.
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