无症状高尿血与肥胖指数之间的关联:西班牙人口的横截面研究
Carmen Sánchez-Bacaicoa1, Esperanza Santano-Mogena2, Sergio Rico-Martín2
1Department of Family Medicine, Hospital of Menorca, 07703 Menorca, Spain.
Nutrients
|November 25, 2023
概括
新的人类指数,如腰与身高的比率 (WHtR),腹部体积指数 (AVI) 和身体圆度指数 (BRI) 是无症状高尿血症的良好预测指标. 这些新型措施为评估心血管风险提供了有价值的见解.
科学领域:
- 心脏病学 心脏病学
- 人类测量学 人类测量学.
- 代谢健康 代谢健康
背景情况:
- 无症状的高尿血是独立的心血管风险因素.
- 新型的人类指数正在成为BMI和WC等传统措施的替代品,用于评估体重和内脏脂肪.
- 无症状高尿血和较新的人类指数之间的关系尚未得到充分证实.
研究的目的:
- 调查无症状高尿血和各种人体指数 (包括新型和传统指数) 之间的关联.
- 为了确定哪些人体指数与无症状高尿素血症独立相关.
- 评估这些指数对无症状高尿路血症的预测潜力.
主要方法:
- 对1094名参加心血管风险咨询的西班牙人进行分析.
- 测量传统和新型人类指数的测量.
- 无症状高尿血的定义基于血清尿酸水平.
主要成果:
- 大多数人体指数在无症状高尿血症患者中显著高.
- 在多变量分析中,腰与身高的比率 (WHtR),腹部体积指数 (AVI) 和身体圆度指数 (BRI) 独立地与无症状高尿素血症相关.
- WHtR,AVI和BRI显示了曲线下最大的面积 (AUC),表明了强大的预测值.
结论:
- WHtR,AVI和BRI独立且积极地与无症状的高尿血症有关.
- 这些新型的人类指数显示出作为无症状高尿血症的有效预测指标的希望.
- 这些发现表明,使用这些措施可以改善心血管风险分层的潜力.
相关概念视频
Obesity
507
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
507
Cholesterol: Significance and Regulation
555
Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Considering cholesterol and...
555
Genome-wide Association Studies-GWAS
13.5K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
13.5K


