在非酒精性脂肪性肝病中的饮食和营养干预在儿科中
Camila Farías1, Camila Cisternas1, Juan Cristobal Gana2
1Department of Nutrition, Faculty of Medicine, Universidad de Chile, Santiago 8380453, Chile.
Nutrients
|November 25, 2023
概括
儿童非酒精性脂肪肝 (NAFLD) 最好通过改变生活方式,包括饮食和运动来管理. 需要进一步的研究来证实特定营养素对儿科NAFLD治疗的益处.
科学领域:
- 儿科胃肠病学和肝病学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是儿科中最常见的慢性肝病.
- 儿童和青少年的肥胖症显著增加了NAFLD的发病率和进展风险.
- 目前的儿科NAFLD治疗缺乏经批准的药物疗法,强调生活方式干预.
研究的目的:
- 审查当前关于治疗儿科NAFLD的科学证据.
- 要突出有效的生活方式的修改,专注于饮食和营养策略.
- 确定特定的营养素和生物活性化合物用于儿童的NAFLD管理.
主要方法:
- 在多个数据库中进行了文献综述.
- 包括专注于儿童NAFLD饮食和/或营养干预措施的研究.
- 分析了低碳水化合物,低糖,低果糖和低脂饮食等干预措施.
主要成果:
- 改变生活方式,包括饮食和运动,是儿科NAFLD的主要建议.
- 研究的饮食缺乏碳水化合物,自由糖,果糖和脂质.
- 检查了涉及omega-3脂肪酸 (EPA/DHA),氨基酸,囊胺,维生素和益生菌的营养干预措施.
结论:
- 生活方式的改变是儿科NAFLD管理的基石.
- 具体的营养策略显示出希望,但需要进一步调查.
- 需要更多的研究来确定个别营养素和生物活性化合物的有效性在儿童中NAFLD.
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