在沙特阿拉伯对结肠直肠癌发病率模式的全面回顾性分析
Ahmed M Basudan1, Abdulrahman Mohammed Basuwdan2, Manal Abudawood1
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh 12372, Saudi Arabia.
Life (Basel, Switzerland)
|November 25, 2023
概括
结肠直肠癌 (CRC) 发病率在沙特阿拉伯急剧上升,在所有年龄组和性别中都观察到显著增加. 紧急的公共卫生干预,包括加强查和预防策略,对于应对这一日益增长的挑战至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 结肠直肠癌 (CRC) 是沙特阿拉伯的主要癌症,造成严重的公共卫生问题.
- 现有的资源不足以评估该地区的CRC负担.
- 了解发病率趋势对于有效的资源配置和卫生政策制定至关重要.
研究的目的:
- 分析沙特阿拉伯2001年至2018年的结直肠癌发病率趋势.
- 通过年龄,性别和行政区域来检查这些趋势.
- 将沙特阿拉伯的CRC发病率趋势与全球数据进行比较.
主要方法:
- 来自沙特癌症登记处 (2001-2018) 的结直肠癌发病率数据的回顾性分析.
- 加入点回归分析以确定发病率的时间趋势.
- 计算和分析了年龄标准化发病率 (ASR) 和年均百分比变化 (APC).
主要成果:
- 结肠直肠癌病例增加了335.6%,占所有癌症病例的12.2%.
- 总体年龄标准化发病率 (ASR) 增加了152%,区域差异显著 (利雅得和东部地区最高).
- 年度百分比变化表明了令人担忧的上升趋势,特别是在老年人群中,超过了全球平均水平.
结论:
- 在沙特阿拉伯,结肠直肠癌的发病率正在惊人地增加,预计将继续上升.
- 发病率和病例数量的显著增加凸显了改善查和预防计划的迫切需要.
- 有针对性的公共卫生战略对于减轻王国日益增长的结直肠癌负担至关重要.
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