碳水化合物核心外电喷式微囊,增强维生素A棕酸盐的氧化稳定性
Elnaz Z Fallahasghari1, Marie Højgaard Lynge1, Emma Espholin Gudnason1
1DTU-Food, Research Group for Food Production Engineering, Laboratory of Nano-BioScience, Technical University of Denmark, Kemitorvet B202, 2800 Kgs. Lyngby, Denmark.
Pharmaceutics
|November 25, 2023
概括
使用电喷剂将维生素A棕酸盐 (AP) 封装在核心外矩阵中,保护其免受氧化. 素蛋白水解剂和耐药的麦芽素显著增强了这种氧化稳定性.
科学领域:
- 食品科学 食品科学 食品科学
- 营养科学 营养科学
- 材料科学 材料科学 材料科学
背景情况:
- 维生素A棕酸 (AP) 是必不可少的,但容易氧化.
- 有效的封装对于保持其稳定性和生物可用性至关重要.
- 氧化降解降低了维生素A补充剂和强化食品的有效性.
研究的目的:
- 为了评估被封装在核心外碳水化合物矩阵中的维生素A棕酸盐 (AP) 的氧化稳定性.
- 调查各种添加剂对封装AP稳定性的影响.
- 优化封装技术,以增强维生素A的保护.
主要方法:
- 同轴电喷技术用于制造核心外微囊.
- 差分扫描热量计 (DSC) 用于热分析.
- 拉曼和减弱的总反射率-里埃变换红外光谱 (ATR-FTIR) 用于化学分析.
主要成果:
- 核心外碳水化合物矩阵有效地减少了AP在表面的暴露,提高了保护.
- 核心中的素蛋白水解剂和外中的耐药麦芽素为AP提供了最佳的氧化保护.
- 使用乙醇作为溶剂增加了蛋白质的疏水性,提高了抗氧化能力.
结论:
- 同轴电喷剂是一种可行的方法,可以创建稳定的维生素A棕酸盐微囊.
- 特定的添加剂,如 kazein 蛋白质水解剂和耐性马尔托德,显著提高氧化稳定性.
- 这种封装策略为维生素A在各种应用中的保存提供了一个有希望的方法.
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