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益生菌,益生菌和共生菌-儿童肥胖的研究热点
Reka Borka Balas1, Lorena Elena Meliț1, Ancuța Lupu2
1Department of Pediatrics I, "George Emil Palade" University of Medicine, Pharmacy, Sciences and Technology, Gheorghe Marinescu Street, No. 38, 540136 Târgu Mureș, Romania.
Microorganisms
|November 25, 2023
概括
儿童肥胖与肠道微生物群的变化有关. 虽然一些益生菌在管理肥胖和相关问题方面表现有前途,但结果是混合的,需要进一步研究有效的策略.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 微生物组研究 微生物组研究
- 公共卫生 营养 公共卫生 营养
背景情况:
- 儿童肥胖是一个与代谢综合征,胰岛素耐药性和非酒精性脂肪肝疾病 (NAFLD) 相关的全球健康危机.
- 肠道微生物群成为影响宿主新陈代谢,和和能量平衡的重要因素.
- 早期肠道失调与儿童肥胖倾向的增加有关.
研究的目的:
- 审查肠道微生物组成对儿童肥胖及其相关并发症的影响.
- 评估肠道微生物群在代谢综合征,NAFLD和胰岛素抵抗中的作用.
- 评估益生菌,益生菌和协生菌在治疗儿童肥胖症中的有效性.
主要方法:
- 对有关肠道微生物群和儿童肥胖现有文献的系统审查.
- 分析调查微生物组成与肥胖相关疾病之间的联系的研究.
- 对使用益生菌,益生菌和共生菌的临床试验数据的评估.
主要成果:
- 肠道微生物群的组成可以积极或消极地影响肥胖的发展.
- 某些益生菌 (例如,Lactobacillus rhamnosus bv-77) 可能会降低BMI,并改善肥胖儿童的脂质概况.
- 益生菌,益生菌和共生菌在改善代谢参数方面的有效性是有争议的,需要进一步调查.
结论:
- 肠道微生物群在儿童肥胖及其并发症中起着至关重要的作用.
- 用特定的益生菌向肠道微生物群可能提供治疗途径,但结果各不相同.
- 进一步的研究对于阐明机制和开发儿童肥胖管理的有效,低成本干预措施至关重要.
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