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在MDM2的N终端区域的形态稳定性

Bruno Rizzuti1,2, Olga Abian2,3,4,5, Adrián Velazquez-Campoy2,3,4,5

  • 1CNR-NANOTEC, SS Rende (CS), Department of Physics, University of Calabria, 87036 Rende, Italy.

Molecules (Basel, Switzerland)
|November 25, 2023
PubMed
概括

对于结合瘤抑制剂p53至关重要的MDM2 (N-MDM2) 的N终端区域表现出较低的结构稳定性,并通过多个中间体展开,表明固有的灵活性.

关键词:
MDM2DM2 在线播放一个圆形的二重化.形状稳定性 形状稳定性约束 网络分析 网络分析不同扫描热量计差异扫描热量计.光是一种光.本质上是无序的蛋白质.

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