作为区域测试战略,疫苗接种范围和疫苗类型的函数的COVID-19发病率比例
Areg A Totolian1, Viacheslav S Smirnov1, Alexei A Krasnov1
1Saint Petersburg Pasteur Institute, 197101 St. Petersburg, Russia.
Viruses
|November 25, 2023
概括
根据疫苗类型,COVID-19的发病率有所不同. 使用mRNA疫苗的国家的发病率高于使用载体或全病毒疫苗的国家,即使疫苗接种和检测覆盖率相似.
科学领域:
- 流行病学 流行病学
- 免疫学 免疫学 免疫学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 尽管疫苗接种广泛,但COVID-19流行病对全球健康构成了挑战,不同国家发生率比例存在显著差异.
- 影响这些变化的因素可能包括人口统计,免疫学和流行病学因素.
研究的目的:
- 调查COVID-19发病率比例与全球范围内使用的SARS-CoV-2疫苗类型之间的关系.
- 在本分析中考虑人口和流行病学因素.
主要方法:
- 编制了来自104个国家的人口统计,免疫流行病学和COVID-19数据数据库.
- 收集的数据包括人口指标,测试覆盖率,疫苗接种情况,发病率比例和疫苗类型分布.
- 按人口和疫苗接种覆盖率分层数据,并进行统计分析,考虑测试覆盖率.
主要成果:
- COVID-19病例数与测试覆盖率和mRNA (V1),载体 (V2),/蛋白 (V3) 和全病毒/无活化 (V4) 疫苗的比例有很强的相关性.
- 在病例数和V2,V3和V4疫苗 (分组为非mRNA,Vnmg) 之间观察到逆相关性.
- 最低的发病率比例与V1:Vnmg比率从0:100到30:70,而最大的发病率则与80:20到100:0.0的比率有关. 主要使用mRNA疫苗的国家的发病率高于使用Vnmg疫苗的国家,即使测试和疫苗接种覆盖范围相似.
结论:
- 报告的COVID-19发病率水平受到测试覆盖率,疫苗接种覆盖率以及使用的SARS-CoV-2疫苗类型的影响.
- 主要使用载体和全病毒疫苗的国家与主要使用mRNA疫苗的国家相比,在可比的疫苗接种和测试条件下,发生率比例明显较低.
关键词:
在 COVID-19 疫情中,在COVID-19的发病率比例.在SARS-CoV-2群体免疫系统中.针对SARS-CoV-2的测试覆盖范围针对SARS-CoV-2的疫苗接种范围在SARS-CoV-2疫苗中使用.更多相关视频
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