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在以色列爆发了帕尔沃病毒B19疫情

Tal Patalon^1,2, Yaki Saciuk¹, Daniel Trotzky^3,4

¹Kahn Sagol Maccabi (KSM) Research & Innovation Center, Maccabi Healthcare Services, Tel Aviv 68125, Israel.

|November 25, 2023

概括

以色列正在经历其最大的人类帕沃病毒B19 (B19V) 疫情,在2023年病例显著增加,特别是在孕妇和学龄儿童中. 需要公共卫生战略来应对这种广泛的病毒感染.

科学领域:

病毒学病毒学
流行病学流行病学
公共卫生公共卫生

背景情况:

人类帕沃病毒B19 (B19V) 呈现出多样化的临床谱,从无症状感染到严重的结果,如胎儿水和怀孕期间的损失.
了解B19V的发病率对于公共卫生干预至关重要,特别是考虑到它对弱势群体的潜在影响.

研究的目的:

分析以色列B19V感染的发病率和趋势.
在重大爆发期间识别与B19V感染相关的人口和社会经济因素.
为公共卫生政策提供有关B19V查和干预的信息.

主要方法:

对以色列270万个人的匿名电子病历进行了回顾性分析 (2015年1月 - 2023年9月).
应用一个具有波桑分布的通用线性模型来计算发病率比率 (IRR),调整混因子.
数据按年,年龄组,社会经济地位 (SES) 和社会部门分层分类.

主要成果:

2023年观察到B19V发病率大幅增加,调整后的IRR与前几年相比为6.6,与2020-2022年相比为9.21.
典型的B19V感染季节性在2023年减少.
孕妇在B19V诊断中表现出最显著的增加 (2023年调整后的IRR为11.47),主要是在头三个月. 感染在学龄儿童 (6-11岁) 中最常见.
患有高SES的个体更频繁地感染. 阿拉伯人口的B19V阳性可能性较低,即使对SES进行调整.

结论:

以色列目前正面临着前所未有的,长期的B19V疫情.
这些发现强调了政策制定者需要考虑针对性查的必要性,特别是对于像孕妇这样的高风险群体.
解决潜在的健康不平等问题需要进一步研究和针对较低SES人口和特定社会部门的干预策略.

关键词:

B19V B19V B19V B19V B19V B19V B19V B19V B19V B19V B19V B19 人类帕沃病毒B19 在COVID-19后的传染病.健康的社会决定因素

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