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探索表面活性剂对二氧化纳米颗粒与生物分子相互作用的影响

Shagufta Khan1, Prairna Balyan2, Ahmad Ali2

  • 1Department of Chemistry, University of Mumbai, Mumbai, India.

Journal of biomolecular structure & dynamics
|November 25, 2023
PubMed
概括

这项研究表明二氧化纳米粒子 (MnO2 NPs) 如何与DNA和蛋白质相互作用. 像Tween 20这样的表面活性剂提高了MnO2 NP的稳定性和生物相容性,提高了它们的应用潜力.

关键词:
BSA) 的使用情况.MnO2 没有NP.半氨酸的反应活性雌激酶活动的酶活性.表面活性剂是什么 表面活性剂是什么热力学因素是热力学因素.重要的生物分子 (DNA)

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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