来自心脏CT扫描的骨矿物质密度:使用对比增强扫描进行机会性查
Andia Cheneymann1, Josephine Therkildsen2, Simon Winther1
1Department of Cardiology, Gødstrup Hospital, Herning, Denmark.
概括
增强对比度的CT扫描显著高估了骨矿物质密度 (BMD),导致骨质疏松症风险的错误分类. 在使用这些扫描用于机会性BMD查之前,调整至关重要.
科学领域:
- 放射学 放射学是一门学科.
- 骨质疏松症研究 骨质疏松症研究
- 医学成像分析 医学成像分析
背景情况:
- 骨质疏松症经常被诊断不足,并且经常与其他疾病同时发生.
- 使用计算机断层扫描 (CT) 扫描进行低骨矿物密度 (BMD) 的机会性查是一种公认的策略.
- 胸部CT扫描,通常用于心脏成像,包括脊椎,使它们适合BMD估计.
研究的目的:
- 调查静脉注射对比剂对胸部BMD测量的影响.
- 为了确定对比度增强是否会影响心脏CT扫描中的BMD评估.
- 评估不同对比触发水平对 BMD 测量的影响.
主要方法:
- 使用异步校准的定量CT测量BMD.
- 在对比剂施用前和施用后,通过心脏CT扫描评估胸部BMD.
- 使用对比度触发水平为130和180的霍恩斯菲尔德单位 (HU) 来进行测量.
主要成果:
- 对比剂的使用导致胸部 BMD 的平均值显著增加 (116±33 mg/cm3 到 130±38 mg/cm3).
- 24%的参与者在使用对比度增强扫描时错误地分类了他们的BMD状态.
- 与较低的触发水平相比,较高的对比触发水平导致BMD显著增加.
结论:
- 与对比度增强的CT扫描大大高估了胸部 BMD,可能导致误诊.
- 对比方案触发水平显著影响BMD测量.
- 使用对比增强CT查BMD临床实施需要对比效应进行调整.
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