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Updated: Jul 10, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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物理DAT:一个基于生理学的药物动力学模型,用于解开使用PhysPK®的溶解,过渡和吸收过程

Marina Cuquerella-Gilabert1, Javier Reig-López2, Jenifer Serna3

  • 1Department of Pharmacy and Pharmaceutical Technology and Parasitology, University of Valencia, Valencia, Spain; Interuniversity Research Institute for Molecular Recognition and Technological Development, Polytechnic University of Valencia-University of Valencia, Valencia, Spain; Simulation Department, Empresarios Agrupados Internacional S.A., Madrid, Spain.

Computer methods and programs in biomedicine
|November 25, 2023
PubMed
概括

这项研究开发了一种机械模型 (Phys-DAT) 来预测口服药物吸收,证明其准确性和可靠性与BCS I和II药物的现有生理学基础药理动力学 (PBPK) 软件相提并论.

关键词:
这位女士是LADME.莫姆,莫姆,莫姆,莫姆,莫姆PBPKK PBPK 的意思是什么意思吸收 吸收 吸收 吸收

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