赫西丁的手术前应用,以减少在分娩后剖腹产感染 (实用):一项随机临床试验
Chelsea A DeBolt1, Manasa G Rao1, Leslie Warren1
1Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Health System and Icahn School of Medicine at Mount Sinai, New York.
American journal of perinatology
|November 25, 2023
概括
在手术前使用赫西丁葡萄酸酸腹布和阴道擦拭剂并没有减少手术部位感染 (SSI) 在分娩后接受剖腹产的患者. 这种组合疗法在预防SSI或其他伤口并发症的标准护理方面没有显著的益处.
科学领域:
- 产科和妇科 产科和妇科
- 预防传染病 预防传染病
- 外科手术的安全性
背景情况:
- 手术部位感染 (SSI) 是剖腹产后的一个重大问题.
- 预防策略旨在减少SSI的发生率,并改善患者的治疗结果.
- 赫西丁葡萄酸盐是用于皮肤制备的广泛使用的消毒剂.
研究的目的:
- 为了评估手术前素酸盐 (CHG) 结合的腹部布和阴道擦拭剂在剖腹产后减少SSI的疗效.
- 为了比较CHG干预组和标准护理组之间SSI和其他伤口并发症的发生率.
主要方法:
- 一个单一中心的随机临床试验,涉及319名在分娩后接受剖腹产的患者.
- 患者被随机分配1:1接受CHG腹部布加阴道擦拭或标准护理.
- 主要结局是产后6周SSI (包括子宫内膜炎) 的发生率;次要结局包括其他伤口并发症和再入院.
主要成果:
- 在产后6周 (p=0.65) 的CHG组 (6.6%) 和标准护理组 (5.3%) 之间没有观察到SSI和子宫内膜炎率的统计学上显著差异.
- 二次结果,包括其他伤口并发症和医院再入院,在两组之间也相似.
- 母亲人口特征在两组之间没有显著差异.
结论:
- 在手术前使用2%的基酸腹巾和4%的基酸阴道擦拭剂的组合似乎没有降低经过分娩试验后剖腹产中SSI的风险.
- 目前的证据不支持在这种患者群体中常规使用这种特定的CHG组合协议来预防SSI.
- 可能需要进一步的研究来探索剖腹产的替代性或优化的消毒剂协议.
相关概念视频
01:23Hand hygiene
3.3K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.3K
01:29Local Anesthetics: Clinical Application as Epidural Anesthesia
436
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
436