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Updated: Jul 10, 2025

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氨酸15可以防止MMP-9引起的香烟烟雾引起的上皮层介质细胞转化

Wensi Zhu1,2,3, Linxiao Han1,2,3, Yuanyuan Wu1,2,3

  • 1Department of Pulmonary and Critical Care Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital, Fudan University, 180 Fenglin Rd, Shanghai, 200032, China.

Respiratory research
|November 25, 2023
PubMed
概括

素15 (Krt15) 通过调节气道重塑和炎症,在慢性阻塞性肺病 (COPD) 中起着保护作用. 缺乏Krt15会加剧COPD的症状,这表明Krt15是潜在的治疗点.

关键词:
气道改造 气道改造 气道改造慢性阻塞性肺病是一种慢性阻塞性肺病.炎症透的透可以引起炎症.矩阵金属蛋白酶-9的作用

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Matrix metalloproteases (MMPs) are enzymes involved in the hydrolysis of proteins and glycoproteins of the extracellular matrix. MMPs are essential for the migration and proliferation of cells through the dense matrix network, throughout embryonic development, and throughout morphogenesis. The first MMP activity discovered was a collagenase in a tadpole's tail undergoing metamorphosis. The active collagen deposition and modifications lead to the morphogenesis of tadpoles into the adult...
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