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Updated: Jul 10, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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Published on: November 14, 2017

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使用基因多基因风险评分识别与阿尔茨海默病相关的基因

Dongbing Lai1, Michael Zhang1, Rudong Li1

  • 1Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.

Journal of Alzheimer's disease : JAD
|November 26, 2023
PubMed
概括

这项研究使用基因多基因风险评分 (PRS) 识别了新的阿尔茨海默病 (AD) 基因,并优先考虑针对这些基因的药物,以提高疗效. 这种方法有效地发现了新的AD相关基因和潜在的治疗点.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在SNP的遗传性.基因共同表达模块是基因的共同表达模块.基于基因的多基因风险评分.基因向药物是一种药物.蛋白质与蛋白质相互作用网络.

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