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Updated: Jul 13, 2026

Directed Evolution Method in Saccharomyces cerevisiae: Mutant Library Creation and Screening
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在基于OptKnock框架的Saccharomyces Cerevisiae中改善烯酸生产

Xiaohan Li1, Bing Hu1

  • 1School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, People's Republic of China.

Studies in health technology and informatics
|November 26, 2023
PubMed
概括

使用基因组规模模型和OptKnock的代谢工程改善了Saccharomyces cerevisiae中的酸 (OA) 生产. 在LK2和LK5菌株中,基因淘汰显著增加了OA产量,证明了微生物细胞工厂的有效方法.

关键词:
流量平衡分析分析流量平衡分析基因组规模的代谢网络模型油酸是什么? 油酸是什么?这是OptKnock的敲门.

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