[患有AKI的癌症患者的脏替代疗法]
Marco Pozzato1, Roberta Fenoglio1, Nunziante Caruso1
1University Center of Excellence on Nephrological, Rheumatological and Rare Diseases (ERK-net, ERN-Reconnect and RITA-ERN Member) including Nephrology and Dialysis Unit and Center of Immuno-Rheumatology and Rare Diseases (CMID), Coordinating Center of the Interregional Network for Rare Diseases of Piedmont and Aosta Valley (North-West Italy), San Giovanni Bosco Hub Hospital, ASL Città di Torino and Department of Clinical and Biological Sciences of the University of Turin, Turin, Italy.
急性损伤 (AKI) 在癌症患者中很常见,随着时间的推移,风险会增加. 早期的多学科护理和适当的置换疗法,如持续置换疗法 (CRRT),对于管理这种并发症至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 在瘤学瘤学.
- 临界护理医学 临界护理医学
背景情况:
- 急性损伤 (AKI) 是癌症患者常见的并发症,具有重大风险.
- 癌症诊断后,AKI的发病率上升,重症患者通常需要脏替代疗法 (RRT).
- 癌症患者中AKI的原因是多因素的,包括血液动力学问题,癌症相关因素,代谢并发症和治疗方法.
研究的目的:
- 突出癌症患者中AKI的患病率和原因.
- 强调预防策略和诊断评估功能.
- 讨论多学科瘤瘤学方法和RRT方式的关键作用.
主要方法:
- 对癌症患者AKI现有文献的综述.
- 讨论诸如补水和非毒性药物使用等预防措施.
- 诊断工具的分析,包括功能测试,成像和活检.
- 评估各种RRT方式 (IHD,PIRRT,CRRT) 和抗凝血策略 (RCA).
主要成果:
- 在癌症诊断后的第一年和第五年,AKI风险显著增加.
- 40%的重症癌症患者需要RRT.
- 区域酸盐抗凝剂 (RCA) 的最佳电路抗凝剂对于CRRT疗效至关重要.
- 多学科评估和及时启动RRT是必不可少的.
结论:
- 预防策略和警监测功能是最重要的.
- 多学科的瘤瘤学方法对于管理癌症患者的AKI至关重要.
- 优化RRT,特别是CRRT与RCA,可以改善结果并降低死亡率.
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