儿科后部可逆脑病综合征:MR成像特征可以预测非瘤患者的结果吗?
Mohamad Gamal Nada1, Yasmin Ibrahim Libda1, Mahmoud M Gohary2
1Radiology Department, Faculty of Human Medicine, Zagazig University, Zagazig, Egypt.
European journal of radiology
|November 26, 2023
概括
在儿科后部可逆脑病综合征 (PRES) 中,在MRI上扩散限制和出血是不良结果的关键预测因素. 这些发现有助于对非瘤病例的早期风险评估.
科学领域:
- 神经学 神经学
- 儿科成像学 儿科成像学
- 放射学 放射学是一门学科.
背景情况:
- 后部可逆脑病综合征 (PRES) 是一种影响儿童的神经疾病.
- 确定预测儿科PRES不良结果的因素对于及时干预至关重要.
研究的目的:
- 为了识别磁共振 (MR) 成像特征,这些特征可以预测患有非瘤性PRES的儿科患者的不良临床结果.
- 确定特定MR发现在确定患者预后方面的意义.
主要方法:
- 对被诊断患有PRES的儿科患者进行了六年后期的回顾.
- 临床结果使用修改的兰金分数 (好与差) 来进行分类.
- 使用单变量和多变量分析对结果组之间的临床和MR特征的比较.
主要成果:
- 其中包括141名儿科患者.
- 性综合征,焦点缺陷,更长的住院时间和机械通风与糟糕的结果有关.
- 显著与糟糕结果相关的MR发现包括深灰质核,小脑,细胞毒性,出血和严重的PRES模式. 在多变量分析中,细胞毒性胀和出血仍然是独立的预测因素.
结论:
- 初始MRI扫描时的扩散限制和出血是非瘤儿科PRES中不良结果的独立预测因素.
- 这些MR发现对于患病儿童的预后和管理策略至关重要.
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