改善抗生素获取的战略以及中低收入国家的前进之路
Himika Wasan1, K H Reeta1, Yogendra Kumar Gupta2,3
1Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India.
The Journal of antimicrobial chemotherapy
|November 26, 2023
概括
全球抗生素危机需要创新和投资. 改善获得基本抗生素的机会,特别是在低收入国家,需要通过新的战略解决经济和基础设施障碍.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 制药创新 制药创新 制药创新
背景情况:
- 抗生素显著增加了预期寿命,但由于抗生素耐药性的增加而面临挑战.
- 缺乏有效的抗生素是全球主要的健康威胁,增加感染死亡率.
研究的目的:
- 在全球范围内审查抗生素获取的主要障碍.
- 探索拟议和实施的模型,以减轻抗生素可访问性问题.
- 建议改善低收入和中等收入国家 (LMICs) 获得抗生素的方法.
主要方法:
- 关于抗生素获取障碍和缓解策略的文献综述.
- 对各种访问模式的分析,包括进入市场的奖励和订阅模式.
- 讨论全球获取计划及其在抗生素获取方面的作用.
主要成果:
- 在LMICs中普遍获得抗生素的重大障碍包括不良的经济激励,监管障碍和卫生基础设施不足.
- 目前正在实施各种创新模式和全球计划,以改善抗生素获取.
- 全球集体努力表明,在抗生素开发和批准方面取得了一些进展.
结论:
- 解决抗生素危机需要对研究,开发和市场可行性进行大量投资.
- 创新的获取模式和全球伙伴关系对于确保全球平等获得必需抗生素至关重要.
- 需要有针对性的战略,以改善在LMICs获得新型和仿制抗生素的机会.
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