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作为选择性阻断阿尔多酶A的α-葡萄糖衍生物:计算机辅助结构优化和对HCC的影响

Qian-Han Xiao1, Ze-Zhi Li1, Li Ren1

  • 1Shaanxi Key Laboratory of Natural Products & Chemical Biology, School of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.

Carbohydrate polymers
|November 26, 2023
PubMed
概括

硫酸阿尔法-D-葡萄糖,如SHDPS-4II,显示增强的结合阿尔多酶A (ALDOA). 这些改性化合物在体外和体内有效抑制肝细胞癌 (HCC) 细胞生长,提供了一个有前途的抗HCC策略.

关键词:
阿尔多酶A是一种葡萄糖是一种葡萄糖.肝细胞癌是肝细胞癌.霍洛特里奇亚二法利亚 (Holotrichia diomphalia) 是一种的植物.硫酸盐衍生物的硫酸盐衍生物.

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