与代谢功能障碍相关的脂肪性肝病患者心血管风险的管理
Anders Mellemkjær1, Mikkel Breinholt Kjær1, David Haldrup1
1Department of Hepatology & Gastroenterology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
European journal of internal medicine
|November 26, 2023
概括
与代谢功能障碍相关的脂肪性肝病 (MASLD),以前称为NAFLD,增加了心血管疾病 (CVD) 的风险. 对MASLD患者进行心血管疾病的查,以及对肥胖和糖尿病等危险因素的管理,对于降低死亡率至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 心脏病学 心脏病学
- 代谢疾病 代谢疾病
背景情况:
- 代谢功能障碍相关的脂肪性肝病 (MASLD) 取代了非酒精性脂肪性肝病 (NAFLD),因为它与代谢综合征有很强的联系.
- 患有MASLD的患者患有心血管疾病 (CVD) 的风险和死亡率增加.
研究的目的:
- 提供有关MASLD中心血管疾病的病理生理学和风险因素的最新信息.
- 推MASLD患者心血管疾病的查方案和治疗策略.
主要方法:
- 审查关于MASLD和CVD的当前文献.
- 在MASLD患者中应用SCORE2系统进行心血管疾病风险评估.
- 关于心血管疾病风险因素的生活方式干预和药物治疗的指导.
主要成果:
- 心血管疾病是MASLD患者的主要死亡原因.
- 减肥,地中海饮食,他类药物和抗高血压药物是推的治疗方法.
- 在MASLD中建议使用SCORE2系统进行心血管疾病查.
结论:
- MASLD显著增加心血管疾病的风险,需要积极的查和管理.
- 改变生活方式和向治疗对于减轻MASLD的心血管疾病发病率和死亡率至关重要.
- 肥胖和2型糖尿病 (T2DM) 的患病率上升可能会增加MASLD和CVD病例,需要加强预防策略.
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