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Updated: Jul 10, 2025

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低氧诱导的PLOD2通过调节依赖EGFR的AKT通路激活促进清细胞细胞癌的进展

Tao Liu1, Wan Xiang2,3, Zhizhuang Chen1

  • 1Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan, China.

Cell death & disease
|November 26, 2023
PubMed
概括

缺氧在清细胞细胞癌 (ccRCC) 中提高PLOD2表达,推动瘤生长和转移. 通过使用米诺西迪尔抑制PLOD2,通过向EGFR/AKT通路,对ccRCC治疗有希望.

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