招募方法,包容和成功参与使用生态瞬间评估的纵向临床试验
Norman Porticella1, Julie S Cannon2, Chung Li Wu3
1Department of Communication, Cornell University, Ithaca, NY, USA.
概括
积极招募健康试验提高了多样性,但可能会降低保留和任务完成率. 研究人员必须平衡公平包容与参与者参与策略,以获得更好的结果.
科学领域:
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
- 临床试验方法论 临床试验方法论
背景情况:
- 历史上被边缘化的人群在临床试验中代表性不足,这影响了研究的有效性.
- 积极的招聘策略,就像拦截一样,有望改善代表性.
- 在纵向研究中,在不同人群中保留和坚持存在挑战.
研究的目的:
- 在健康干预试验中比较主动和反应性招聘策略.
- 分析对研究纳入,任务完成和保留的影响.
- 通过使用生态瞬间评估 (EMA) 在试验中招募各种参与者的最佳实践.
主要方法:
- 一个为期14天的随机对照试验的二次数据分析.
- 移动实验室拦截 (主动) 与互联网/传单广告 (反应) 的比较.
- 评估包容率,任务完成率和参与者保留率.
主要成果:
- 积极的招聘增加了收入较低,受教育程度较低,健康素养较高,种族/民族背景多样化的参与者的包容性.
- 积极的招聘与较低的任务完成率和保留率有关,特别是在第二周.
- 记忆和完成的差异并没有通过社会人口统计学特征来解释.
结论:
- 积极的招聘有效地提高了卫生干预研究的多样性.
- 需要额外的资源和策略来应对参与者保留和坚持主动方法的挑战.
- 公平招聘与持续参与之间的平衡对于涉及边缘化群体的成功试验至关重要.
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