一种通过酵母发酵过程提取脂的新方法,以提高皮肤的疗效
Yae-Rin Lee1, Youn Jeong Cha2, Sugyeong Jeong1
1COSMAX BTI R&I Center, Seongnam, South Korea.
概括
生物转化Oji复合物,源自使用生物转化提取的韩国草药,显著提高皮肤水分和屏障功能. 这种创新成分具有强大的抗炎作用,非常适合用于化品应用.
科学领域:
- 植物化学 植物化学
- 生物技术是生物技术.
- 皮肤病学 皮肤病学
背景情况:
- 传统的东方草药具有宝贵的植物化学物质和生物活性.
- 生物转化提取技术为增强草本特性提供了一种新的方法.
研究的目的:
- 用生物转化提取方法在五种韩国传统药草中识别植物化学物质.
- 为了评估由此产生的生物转化Oji复合物的与皮肤相关的疗效.
主要方法:
- 一个两步的生物转化过程,包括用Candida bombicola发酵,然后用五种天然植物发酵.
- 在HaCaT细胞的体外研究评估了与皮肤抗炎,保湿和屏障改善相关的生存能力和mRNA表达.
- 在21名参与者的体内研究评估了4周的抗炎,保湿和皮肤屏障效应.
主要成果:
- 生物转化显著增加了氨基酸和脂质含量,确定了23种黄类.
- 生物转化Oji复合物是无毒的,并在体外和临床研究中显示出显著的抗炎,保湿和皮肤屏障改善.
结论:
- 生物转化Oji复合物表现出皮肤友好性质,具有显著的抗炎,补水和增强屏障的作用.
- 这项研究支持使用生物转化Oji复合物作为化品和护肤品中的活性成分.
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