介绍数据科学到N-of-1设计,统计,用例,未来,以及号"N-of-1"试验
Karina W Davidson1, Ying Kuen Cheung2, Ciarán P Friel1
1Institute of Health System Science, Feinstein Institutes for Medical Research, Northwell Health; Manhasset, NY.
个性化 (N-of-1) 试验需要患者参与. 研究人员提出了一个新的,消费者友好的名称,以改善患者参与这种基于证据的方法.
科学领域:
- 健康数据科学和统计学
- 临床试验设计 临床试验设计
- 以患者为中心的研究
背景情况:
- 个性化 (N-of-1) 试验提供量身定制的医学见解,但严重依赖患者参与.
- 目前的术语是"N-of-1试验",可能会阻碍患者的参与和招募.
- 有效实施需要患者的志愿服务和积极参与临床服务.
研究的目的:
- 为个性化 (N-of-1) 试验引入方法,数据管理,设计和用例.
- 探索试验命名对患者参与的影响.
- 为个性化 (N-of-1) 试验提出一个更容易获得的名称,以提高患者参与度.
主要方法:
- 对个性化 (N-of-1) 试验的方法,数据类型,管理,设计和应用进行审查.
- 分析患者对术语"N-of-1试验"的反.
- 对个性化试验提出了一个新的,消费者友好的术语.
主要成果:
- 个性化 (N-of-1) 试验需要大量的患者参与才能成功实施.
- 标签"N-of-1试验"可能不会有效地鼓励患者参与.
- 建议使用一种更为消费者友好的名称,以促进患者参与.
结论:
- 患者参与对于个性化 (N-of-1) 试验的成功至关重要.
- 修改术语可以改善患者的招募和坚持.
- 一个新的称旨在促进对个性化研究的更大理解和参与.
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