对三种阿育吠陀配方进行人体评估:在Raillietina sp. 中进行传输电子显微镜研究. (科斯托达) 的意思
Risa Parkordor Chen1, Amar Deep Soren2, Arun K Yadav1
1Department of Zoology, North-Eastern Hill University, Shillong, 793022 India.
概括
艾尔韦达配方Krimimudgar Ras在实验室中显示出对禽类虫有显著的抗虫作用. 传输电子显微镜揭示了广泛的超结构损伤,表明其作为有效的抗寄生虫剂的潜力.
科学领域:
- 兽医寄生虫学 兽医寄生虫学
- 传统印度医学 传统印度医学
- 电子显微镜电子显微镜
背景情况:
- 阿育吠陀医学是一种古老的印度系统,需要科学验证才能有效.
- 像Raillietina sp.这样的家禽鸟类在鸟类种群中构成重大健康和经济挑战.
- 有限的科学证据表明,许多阿育吠陀配方具有抗虫的特性.
研究的目的:
- 为了研究三个阿育吠陀配方的体外杀虫作用:克里米穆德加拉斯,克里米诺尔和比兰加萨夫.
- 评估这些配方在家禽中产生的超结构变化 Raillietina sp. 使用传输电子显微镜 (TEM).
- 为了确定对Raillietina sp.最有效的阿育吠陀配方. 基于观察到的细胞损伤.
主要方法:
- 成人Raillietina sp. 的使用情况. 干被暴露在不同度的Krimimudgar Ras,Kriminol和Birangasav.中.
- 用最高度 (50毫克/毫升) 处理的寄生虫和参考杀虫剂 (praziquantel) 被处理为TEM.
- 超结构分析的重点是微三层,基底层,肌肉,核和线粒体的变化.
主要成果:
- 50毫克/毫升的Krimimudgar Ras导致了最严重的超结构损伤,包括微线层,基底层,肌肉,线粒体和细胞核的破坏.
- 与Krimimudgar Ras.相比,克里米诺尔的损伤不那么明显.
- 比兰加萨夫诱导了对微三层,核和线粒体的破坏性影响,但不如克里米穆德加拉斯那么严重.
结论:
- 克里米穆德加拉斯在体外对Raillietina sp.表现出强烈的杀虫活性. 这就是CESTodes.cestodes.
- 观察到的超结构性变化为Krimimudgar Ras.的疗效提供了机械基础.
- 克里米穆德加拉斯 (Krimimudgar Ras) 显示出作为对家禽寄生虫的潜在天然杀虫剂的潜力.
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