相关实验视频

Updated: Jul 10, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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关于aryl-C ((sp3) 键的亚tropisomerism:在大麻衍生物中的化学驱动的旋转路径

Clément Denhez1, Pedro Lameiras1, Hatice Berber1

  • 1Université de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France. hatice.berber@univ-reims.fr.

Organic & biomolecular chemistry
|November 27, 2023
PubMed
概括

这项研究研究了大麻二醇衍生物,揭示了围绕关键化学键键的有限旋转. 特定的修改影响过渡状态的稳定性,影响分子形状和性质.

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Stereoisomerism of Cyclic Compounds

In this lesson, we delve into the role of ring conformation and its stability, which determines the spatial arrangement and, consequently, the molecular symmetry and stereoisomerism of cyclic compounds. 1,2-Dimethylcyclohexane is used as a case study to evaluate the possible number of stereoisomers. Here, given the multiple (n = 2) chiral centers, there are 2n = 4 possible configurations that lack a plane of symmetry, as the ring skeleton exists in a non-planar chair conformation. In addition,...
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