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Updated: Jul 10, 2025

A Co-culture Method to Investigate the Crosstalk Between X-ray Irradiated Caco-2 Cells and PBMC
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主性纤毛通过TGF-β1信号传递参与辐射诱导的旁观者效应

Pei Qu1,2, Zhiang Shao1,2, Yanan Zhang1,2

  • 1Key Laboratory of Space Radiobiology of Gansu Province & Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.

Journal of cellular physiology
|November 27, 2023
PubMed
概括

主要毛在辐射诱导的旁观者效应 (RIBES) 中发挥着关键作用,通过调节瘤生长因子-β (TGF-β) 信号传递. 这项研究揭示了主要乳毛是如何影响旁观细胞中的DNA损伤的,将乳毛功能与RIBEs联系起来.

关键词:
损伤的DNA会导致DNA受损.在TGF-β1中.电离辐射辐射的电离辐射.主要的纤毛是主要的纤毛.辐射诱导的旁观者效应

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