外体膜氧化用于心脏骤停:什么,何时,为什么,以及如何
Matthew Brandorff1, Clark G Owyang1,2, Joseph E Tonna3,4
1Division of Pulmonary and Critical Care Medicine, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical College, New York, NY, USA.
Expert review of respiratory medicine
|November 27, 2023
概括
身体外心肺复苏 (ECPR) 在专业系统中的精选患者中,可改善耐心性心脏骤停的生存率. 仔细实施和进一步研究对于优化结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 临界护理医学 临界护理医学
- 紧急医疗 紧急医疗
背景情况:
- 自20世纪60年代以来,体外膜氧化 (ECMO) 促进的复苏已经发生了显著的进化.
- 最近的大型观测研究和随机试验越来越关注它的应用.
研究的目的:
- 提供对体外心肺复苏 (ECPR) 的全面审查.
- 涵盖ECPR的历史,术语,电路配置,通道,并发症,选择标准和管理.
- 讨论结果并倡导注册表参与以提高质量.
主要方法:
- 历史数据和最近的大型观测研究的审查.
- 对评估ECPR的随机试验的分析.
- 综合ECPR实施和管理的当前指南和最佳实践.
主要成果:
- 在高度精选的患者和系统中,ECPR可以在耐心性心脏骤停中增加高达30%的存活率.
- 高生存率取决于紧密的协议设置和高体积的环境.
- 最近的试验表明,在控制较少的环境中实施时,有效性降低.
结论:
- 在心脏骤停复苏方面,ECPR代表了破坏性的进步.
- 最佳启动值,实施最佳实践和复苏后护理需要进一步研究.
- 参与国家/国际注册表对于ECPR的持续质量改进和科学发现至关重要.
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