在急性四肢缺血症的开放手术,混合和内血管再血管化后的结果
Nikolaos Konstantinou1, Angeliki Argyriou2, Felicitas Dammer1
1Department of Vascular Surgery, University Hospital LMU Munich, Munich, Germany.
概括
与手术或混合方法相比,急性四肢缺血症 (ALI) 的内血管治疗提供了更好的四肢挽救和生存率. 这项为期10年的研究发现,ET与改善的无截肢生存率和较低的死亡率有关.
科学领域:
- 血管外科 血管外科
- 血管内干预 血管内干预
- 急性四肢缺血的治疗方法
背景情况:
- 急性四肢缺血 (ALI) 呈现出显著的发病率和死亡率.
- 有限的数据存在,比较ALI的手术,混合和内血管治疗方法.
- 需要对ALI治疗结果进行全面的10年分析.
研究的目的:
- 为了比较外科治疗 (ST),混合治疗 (HT) 和内血管治疗 (ET) 对ALI的有效性.
- 为了评估不同的ALI治疗方式的无截肢生存率 (AFS),死亡率,截肢率和重新干预率.
主要方法:
- 在2010-2020年期间接受治疗的395名ALI患者的回顾性比较研究.
- 主要终点:没有截肢的生存率 (AFS). 二级终点:死亡率,重大截肢,重新干预.
- 用多变量比例危险建模来分析结果.
主要成果:
- 与ST和HT相比,内血管治疗 (ET) 显示出明显更好的AFS.
- ET与死亡率明显低于ST和HT.
- 与ST相比,ET的截肢率较低,与HT相比,其截肢率相当.
结论:
- 对ALI的内血管治疗与改善无截肢生存率和降低死亡率有关.
- 在ET,ST和HT组中,再干预率是可比的.
- 对于患有急性四肢缺血症的患者来说,ET是一种有利的治疗选择.
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