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Updated: Jul 10, 2025

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基于基的imidazo[2,1-b]thiazole衍生物:合成,晶体结构,强大的抗癌活性,以及计算研究

Said Dadou1,2, Ahmet Altay3, Cemile Baydere4

  • 1Laboratory of Applied Chemistry and Environment, Faculty of Sciences, Mohammed First University, Oujda, Morocco.

Journal of biomolecular structure & dynamics
|November 27, 2023
PubMed
概括

两种基于石墨烯的新型伊米达佐提亚衍生物,ITC-1和ITC-2,对各种癌症细胞系表现出强大的抗癌活性. 这些化合物通过线粒体通路诱导亡,并显示出作为抗癌药物候选者的有前途潜力.

关键词:
石灰是一种的物质.这是一种抗癌药物.灭症 (apoptosis) 是一种死亡的过程.停靠的对接方式伊米达佐提亚;DFT 在线

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5-HT3 receptor antagonists, such as dolasetron, granisetron (Kytril), ondansetron (Zofran), and palonosetron (Axoli), are crucial in managing chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea. These drugs selectively block 5-HT3 receptors in the visceral vagal and spinal afferent nerves, chemoreceptor trigger zone, and the vomiting center. They have a rapid onset of action and can be given as a single dose before chemotherapy. Ondansetron and granisetron, in particular,...
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