[由于COVID-19大流行 (审查) 的结果,人口加快老龄化
I M Kobelev1, U R Saginbaev1, S A Rukavishnikova1
1Saint-Petersburg State Hospital № 2, 5 Uchebny per., St. Petersburg 194354, Russian Federation,
Advances in gerontology = Uspekhi gerontologii
|November 27, 2023
概括
COVID-19大流行加速了人口老龄化,导致诸如端粒缩短和认知能力下降等有害健康影响. 进一步的研究对于理解和潜在地扭转这些衰老过程至关重要.
科学领域:
- 老年学是指老年学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- COVID-19 疫情对全球健康和社会结构产生了重大影响.
- 新出现的证据表明,SARS-CoV-2感染与加速生物衰老之间存在联系.
研究的目的:
- 总结COVID-19与加速衰老相关的多方面的健康后果.
- 突出需要进一步研究驱动这些衰老效应的机制.
主要方法:
- 文献审查和关于COVID-19和衰老的科学发现的综合.
- 分析与SARS-CoV-2感染相关的报告健康结果.
主要成果:
- COVID-19与端粒缩短,神经退行性和心血管疾病增加,认知障碍和抑郁症有关.
- SARS-CoV-2 感染与早期血管衰老,DeltaAge 加速,以及诸如 I 型素和肌素等生物标志物的升高有关.
- 观察到的影响包括执行功能障碍,痴呆症,残疾和减少对健康行为的参与.
结论:
- SARS-CoV-2 感染有助于在多个生理系统中加速衰老.
- 了解潜在的机制对于开发干预措施来促进流行病后健康的生物衰老至关重要.
- 持续的研究对于解决COVID-19的长期衰老相关后果至关重要.
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