与自闭症谱系障碍患者神经发育改变相关的指纹模式
Klaudia Kyselicová1, Dóra Dukonyová1, Ivan Belica1
1Academic Research Center for Autism, Institute of Physiology, Faculty of Medicine, Comenius University Bratislava, Bratislava, Slovakia.
Developmental psychobiology
|November 27, 2023
概括
指纹图案显示自闭症谱系障碍 (ASD) 的差异. 患有自闭症的男孩表现出更多的双边模式变化,这表明产前发育不稳定可能会影响神经发育.
科学领域:
- 发展生物学 发展生物学
- 神经科学是一个神经科学.
- 遗传学 遗传学 是一个
背景情况:
- 皮肤刻字图案,包括指纹,在孕期早期建立.
- 改变的神经发育,如自闭症谱系障碍 (ASD),可能与发育不稳定有关.
- 指纹模式可以作为ASD的潜在生物标志物.
研究的目的:
- 为了比较ASD男孩与对照者的皮肤刻字图案频率和不对称性.
- 调查指纹模式是否可以表明ASD的发育不稳定性.
主要方法:
- 在67名自闭症男孩和83名对照男孩中比较了指纹图案数量和波动不对称性.
- 使用奇平方测试来分析模式频率差异.
主要成果:
- 患有自闭症的男孩在指纹图案中显示出明显更高的不一致性和双边差异 (p = .0026).
- 观察到图案频率的显著差异,自闭症男孩的环较少,形和形形较多,特别是在右手上.
结论:
- 产前发育对双边指纹模式的影响可能会导致ASD神经发育的改变.
- 指纹分析显示了作为一种非侵入性生物标志物的潜力,用于识别与ASD相关的发育不稳定性.
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