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国际骨髓甲状腺癌分级系统:一个印度的三级护理中心经验

Varnika Rai¹, Anurag Saha¹, Shailee Mehta²

¹Onco-Pathology Department, Gujarat Cancer and Research Institute, Ahmedabad, India.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

|November 27, 2023

概括

国际骨髓甲状腺癌分级计划 (IMTCGS) 有效预测骨髓甲状腺癌 (MTC) 的结果. 通过IMTCGS识别的高度MTC与较差的存活率和远程转移的增加有关.

科学领域:

内分泌学在内分泌学.
在瘤学瘤学.
病理学病理学病理学

背景情况:

骨髓癌 (MTC) 是一种罕见的神经内分泌甲状腺瘤.
国际骨髓甲状腺癌分级方案 (IMTCGS) 有预后意义.
这项研究评估了印度队列中的IMTCGS.

研究的目的:

使用IMTCGS对MTC案件进行分级.
评估IMTCGS在印度研究队列中的预后意义.
根据IMTCGS进行低等级 (LG) 和高等级 (HG) MTC 的比较.

主要方法:

在6年内对32例MTC甲状腺切除术病例进行了回顾性分析.
基于IMTCGS标准的LG和HGMTC的比较.
生存分析包括总生存率 (OS),局部区域自由生存率和远程转移自由生存率 (DMFS).

主要成果:

31.25%的病例是HG MTC,68.75%是LG MTC.
HG MTC患者年龄较大,表现出高度核特征,突出的核细胞和远程转移.
在多变量分析中,IMTCGS与OS (HR 28.30) 和DMFS (HR 15.70) 有显著的关联.

结论:

IMTCGS是一个简单方便的MTC分级系统.
在高级核形态病例中,建议对Ki 67进行IHC和勤奋寻找亡.
HG MTC 队列与较差的 OS 和 DMFRS 有关.

关键词:

评分评分评分评分高等级的高等级的等级.在IMTCGS中,您可以使用IMTCGS.基67指数是指数中的一个.甲状腺中枢癌甲状腺中枢癌线粒分裂 (mitosis) 是一种发生在细胞的过程.尸体消亡 (necrosis) 是一种致死症.

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