营养摄入量与女性不孕症之间的关联:基于NHANES数据库的研究
Xiaowei Ji1, Yao Ye1, Lin Wang1
1Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, PR China.
概括
摄入更多的关键营养素,如维生素A,C,叶酸,,铁和甘,与女性不孕症的风险降低有关. 这些饮食因素可能代表女性可修改的生活方式选择.
科学领域:
- 营养科学 营养科学
- 生殖健康 生殖健康
- 流行病学 流行病学
背景情况:
- 女性不孕症是一个重要的生殖健康问题.
- 饮食模式和营养摄入量越来越被认为是影响生育能力的潜在因素.
- 了解特定的营养物质关联可以为公共卫生策略提供信息.
研究的目的:
- 调查各种营养素摄入量与女性不孕症风险之间的关联.
- 为了确定特定的维生素,矿物质和抗氧化剂,可能有助于预防不孕.
- 探索这些关联如何与体重指数 (BMI) 变化.
主要方法:
- 一项采用2013-2016年国家健康和营养检查调查 (NHANES) 数据的横截面研究.
- 包括1713名生育年龄妇女 (18-45岁).
- 根据BMI进行了多变量逻辑回归和子组分析,以评估营养素与不孕症风险关系.
主要成果:
- 更高的碳水化合物,维生素A,维生素C,,铁,甘和叶酸总的摄入量与女性不孕症的风险较低显著相关 (ORs从0.36到0.55).
- 亚组分析表明,维生素A,维生素C和烯与正常BMI (18.5-24.9 kg/m2) 的女性的不孕症风险降低有关.
- 在BMI>24.9kg/m2的女性中,较高的,铁和叶酸总摄入量表明不孕症风险降低.
结论:
- 特定的营养素摄入量,包括维生素A和C,,铁,甘和叶酸,与女性不孕症的风险降低有关.
- 这些发现突出了可能改变的饮食因素,这些因素可能会影响女性生殖健康.
- 进一步的研究可以探索因果机制和有针对性的营养干预措施.
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