一个新的范式检查在线nocebo效应的远程诱导
Kirsten Barnes1, Kate Nicholls1, Sascha Orlievsky1
1University of New South Wales, School of Psychology.
概括
在线副作用信息可以远程诱导nocebo效应,对健康结果产生负面影响. 针对负面预期是缓解这些不利影响的关键.
科学领域:
- 心理学 心理学 心理学
- 卫生沟通健康沟通
- 行为医学是一种行为医学.
背景情况:
- 在线健康信息普遍存在,但其在产生负面健康结果 (nocebo效应) 中的作用尚未得到充分探索.
- 关于传达的副作用信息如何影响患者体验的实验证据有限.
研究的目的:
- 开发和验证一种新的范式,使用在线副作用信息远程诱导nocebo效应.
- 调查影响nocebo效应的因素,包括信息来源,积极/消极影响和预期.
主要方法:
- 参与者收到了有关低频噪声 (LFN) 益处的信息,有些人警告了副作用.
- 两项研究检查了信息来源和影响调制,随后进行了对预期的综合分析 (N=983).
主要成果:
- 在被警告副作用的参与者中观察到显著的nocebo效应,无论信息来源或积极影响诱导.
- 收到副作用信息减少了积极的健康结果.
- 负面期望调解了nocebo效应,高负面期望阻碍了积极的结果.
结论:
- 在线副作用的最小信息可以远程产生nocebo效应.
- 未来的干预措施应侧重于管理积极和消极的期望,以减少nocebo效应和改善健康结果.
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