伊朗专家在多发性硬化症患者认知障碍患者治疗升级的方法
Fereshteh Ghadiri1, Elnaz Asadollahzadeh1, Zahra Ebadi1
1Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Current journal of neurology
|November 27, 2023
概括
多发性硬化症 (MS) 专家在患者的治疗选择上表现出不佳的共识,即使存在认知障碍. 需要更多的研究来建立关于管理多发性硬化症认知症状的共识指南.
科学领域:
- 神经学 神经学
- 神经免疫学 神经免疫学
- 临床实践 临床实践
背景情况:
- 认知保留是多发性硬化症 (MS) 疾病修饰疗法 (DMT) 的关键结果.
- 了解有关MS治疗策略的专家共识,特别是关于认知功能,至关重要.
研究的目的:
- 评估伊朗多发性硬化症 (MS) 专家关于不同临床情景最佳治疗方法的意见.
- 评估MS患者在不同的身体和认知条件下治疗升级方面的专家协议.
主要方法:
- 一项调查分发给20名多发性硬化专家.
- 专家为6个不同的临床病例场景提供了治疗建议.
- 统计分析,包括kappa协议,用于评估共识.
主要成果:
- 较低的卡帕统计值 (0.16) 表明专家之间对于治疗选择的一致性较差.
- 虽然大多数专家赞成认知障碍治疗升级,但没有达成普遍共识.
- 在各种案例介绍中观察到重大的专业分歧.
结论:
- 在MS专家之间,对于认知障碍患者的最佳治疗策略缺乏共识.
- 目前的临床证据不足以制定明确的指导方针来管理MS认知功能障碍.
- 需要进一步的研究,以根据MS的认知症状做出基于证据的治疗决定.
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