倾向于患有叶的患者发作的因素聚集在一起
Marjan Asadollahi1, Faezeh Maghsudloo2, Leila Simani3
1Epilepsy Monitoring Unit, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Current journal of neurology
|November 27, 2023
概括
在叶 (TLE) 中的发作集群与患者的持续时间,间接性发作发射器 (IED) 的频率或MRI发现无关. 这项研究分析了124名TLE患者,以发现发作的潜在风险因素.
科学领域:
- 神经学 神经学
- 发病学 (Epileptology) 是一个专业的学科.
- 临床神经科学 临床神经科学
背景情况:
- 叶 (TLE) 是一种常见的焦点.
- 被定义为在短时间内发生多次发作的发作集群可以显著影响患者的生活质量.
- 识别TLE中发作集群的风险因素对于有效管理至关重要.
研究的目的:
- 调查叶患者中集群的潜在风险因素.
- 为了确定发作集群和持续时间之间的关联,间接性形放电 (IED) 和脑磁共振成像 (MRI) 发现.
主要方法:
- 对124名连续TLE患者的回顾性横截面研究,这些患者被录取到监测单元 (EMU).
- 收集的数据包括人口统计信息,持续时间,发作频率,IED频率通过头皮脑电图 (EEG) 和MRI发现.
- 发作集群被定义为在24小时内≥3次常见发作>50%的发作事件中,发作间隔小于8小时.
主要成果:
- 50%的TLE患者 (62/124) 经历了集群.
- 在集群和持续时间 (P=0.100) 之间没有发现显著的关联.
- 扣押集群与IED频率 (P=0.764) 或MRI发现 (P=0.112) 没有相关性.
结论:
- 在这组TLE患者中,发作聚类与持续时间没有相关性.
- 脑电图上间歇性发泄物 (IED) 的频率与发作集群不相关.
- 脑部MRI发现,包括 mesial temporal sclerosis,并没有预测TLE中的发作集群.
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