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Updated: Jul 9, 2025

In Vitro Assay to Evaluate the Impact of Immunoregulatory Pathways on HIV-specific CD4 T Cell Effector Function
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由HCMV分泌的糖蛋白gpUL4抑制了TRAIL介导的亡和NK细胞激活

Virginia-Maria Vlachava1, Sepehr Seirafian1, Ceri A Fielding1

  • 1Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.

Proceedings of the National Academy of Sciences of the United States of America
|November 27, 2023
PubMed
概括

人类细胞巨乳病毒 (HCMV) 使用一种新型分泌蛋白,gpUL4,来逃避免疫反应. 这种病毒诱受体通过阻断 TRAIL 来抑制自然杀手 (NK) 细胞活动,作为全身免疫抑制剂.

关键词:
这就是HCMV.在 NK 细胞中.轨道的轨道是一个轨道.

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