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动脉生成指数预测了发生腹腔透析患者的全因和心血管死亡率

Jihong Deng¹, Xingming Tang², Ruiying Tang¹

¹Department of Nephrology, Jiangmen Central Hospital, Jiangmen, China.

Atherosclerosis

|November 27, 2023

概括

无氧原体指数 (AI) 与腹腔透析 (PD) 患者的死亡率增加有关. 更高的AI水平与心血管疾病 (CVD) 和PD人群的整体死亡风险更高显著相关.

科学领域:

腎臟病學 (nephrology) 是一種醫學專業.
心脏病学心脏病学
生物标志物生物标志物

背景情况:

动脉样硬化是腹膜透析 (PD) 患者的主要并发症,增加心血管疾病 (CVD) 风险.
动脉增生指数 (AI) 是已知的动脉样硬化预测指标,但其在PD患者的预后作用尚不清楚.

研究的目的:

研究患有PD的患者中甲基因指数 (AI) 与全因和心血管疾病死亡率之间的关联.
为了确定AI是否可以作为预后标记在这个患者群体的不良结果.

主要方法:

从2006年1月到2018年12月,分析了2682名PD患者的队列.
根据AI四分位数,患者被分为四组.
多变量考克斯回归模型被用来评估AI与死亡率之间的关系.

主要成果:

在35.5个月的中位数随访期间,发生了800例死亡,416例死于心血管疾病.
人工智能和不良结果之间观察到非线性关系.
与最低四分位数 (Q1) 相比,最高AI四分位数 (Q4) 显示所有原因 (HR 1.54) 和心血管疾病死亡率 (HR 1.78) 的危险比率显著增加.

结论:

无气性指数 (AI) 独立地与PD患者全因和心血管疾病死亡率的增加有关.
人工智能可以作为心血管事件和PD患者死亡率的有价值的预后指标.

关键词:

异源性指数 (Atherogenic Index) 是一个指数.心血管疾病是什么心血管疾病死亡率死亡率死亡率腹膜透析是指腹膜透析.

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