阻塞性睡眠呼吸暂停会增加疹和后神经疼痛的风险
Chih-An Wang1, Wen-Che Hsieh2, Tzu-Ju Hsu3
1Division of Respiratory Therapy, Ditmanson Medical Foundation, Chia-Yi Christian Hospital, Chia-Yi, Taiwan.
Postgraduate medicine
|November 27, 2023
概括
阻塞性睡眠呼吸暂停 (OSA) 显著增加患疹 (HZ) 和后神经疼痛 (PHN) 的风险. 患有OSA的患者应该意识到这种增加的风险及其与压力的联系.
科学领域:
- 睡眠医学 睡眠医学
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 慢性疼痛和压力与疹子 (HZ) 的发展有关.
- 阻塞性睡眠呼吸暂停 (OSA) 是一种可能充当压力因素的情况.
研究的目的:
- 调查阻塞性睡眠呼吸暂停 (OSA) 是否增加了HZ和后神经疼痛 (PHN) 的风险.
主要方法:
- 使用国家医疗保险研究数据库 (2000-2017年) 进行的一项回顾性队列研究.
- 匹配了25,211名OSA患者和25,211名对照者的1:1队列.
- 根据年龄,性别,并发症和索引年份进行调整.
主要成果:
- 与对照组相比,患有OSA的患者具有明显更高的HZ (aHR=1.22) 和PHN (aHR=1.36) 的风险.
- 在患有 (aHR=1.17) 和没有 (aHR=1.28) 同病症的患者中,OSA增加了HZ风险.
- OSA显著增加PHN风险,特别是在没有其他并发症的人群中 (aHR=1.68).
结论:
- 阻塞性睡眠呼吸暂停 (OSA) 与疹子 (HZ) 和后神经疼痛 (PHN) 的风险增加有关.
- 诊断为OSA的患者应被告知增加压力的可能性以及随后发展HZ和PHN的风险.
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