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Updated: Jul 9, 2025

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作为MDM2抑制剂的二皮利米丁衍生物

Ali Mehri1, Karim Mahnam2, Hajar Sirous3

  • 1Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Science, Isfahan University of Medical Science, Isfahan, Iran.

Chemical biology & drug design
|November 27, 2023
PubMed
概括

研究人员设计了Monastrol衍生品作为MDM2抑制剂来对抗癌症. 在和体外研究表明,5d化合物有效抑制MDM2,重新激活p53并显示出瘤治疗的潜力.

关键词:
二皮里米丁 (DHPM) 是一种这是一种MDM2抑制剂.细胞毒性 细胞毒性在的中.

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