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OVOL2 维持了产后胸膜上皮细胞的身份

Xue Zhong1, Nagesh Peddada1, Jianhui Wang1

  • 1Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, 75390-8505, USA.

Nature communications
|November 27, 2023
PubMed
概括

卵子2蛋白对于维持胸膜上皮细胞 (TEC) 身份和出生后的功能至关重要. 它的缺乏导致T细胞淋巴缺血,因为它破坏了表观遗传调节,并促进了TEC中介酶状态.

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