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Updated: Jul 9, 2025

Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts
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Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts

Published on: September 1, 2018

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活体CS1-OKT3双特异性双价抗体武装效应性T细胞介导细胞免疫力对抗多发性髓瘤

Dennis Awuah1, Lin Li2, Lindsay Williams2

  • 1T Cell Therapeutics Research Laboratory, Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA, 91010, USA.

Scientific reports
|November 27, 2023
PubMed
概括

针对CS1的双特异性T细胞参与抗体 (bsAbs) 对多发性骨髓瘤 (MM) 是有前途的. CS1-dbBiTE武装的T细胞有效地杀死CS1-表达的MM瘤,在临床前模型中减少瘤负担.

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