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Updated: Jul 9, 2025

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人类中性基酶1 (hSMPD2) 的催化机制的分子基础

Jingbo Yi1, Boya Qi1, Jian Yin1

  • 1Ministry of Education Key Laboratory of Protein Science, Tsinghua-Peking Joint Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

Nature communications
|November 27, 2023
PubMed
概括

研究人员解决了人体中性甲基酶1 (SMPD2) 的结构,揭示了其二元结构和甲基氨酸水解的关键残留物. 这为陶胺生产,脂质代谢和潜在的癌症治疗提供了洞察力.

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