心血管并发症不会影响前列腺动脉栓塞 (PAE) 结果:英国国家ROPE注册表的回顾性分析
Ganesh Vigneswaran1,2, Drew Maclean1, Neel Doshi1,2
1Department of Interventional Radiology, University Hospital Southampton, Southampton, UK.
Cardiovascular and interventional radiology
|November 27, 2023
概括
心血管并发症不会显著影响前列腺动脉栓塞 (PAE) 在良性前列腺激增症 (BPH) 患者的结果. 无论这些常见的健康状况如何,都可以获得成功的PAE症状缓解.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 干预性放射学 干预性放射学
- 心血管医学 心血管医学
背景情况:
- 前列腺动脉栓塞 (PAE) 是症状良性前列腺增生 (BPH) 的首要治疗方法.
- 心血管风险因素可能会影响PAE治疗结果和患者选择.
- 调查并发症对PAE疗效的影响对于临床决策至关重要.
研究的目的:
- 评估心血管并发症是否会影响BPH的PAE结果.
- 为了确定像高血压,糖尿病和CAD这样的常见风险因素是否会影响PAE的成功.
主要方法:
- 英国前列腺动脉栓塞注册 (UK-ROPE) 数据库的回顾性分析.
- 包括有记录的病史 (高血压,糖尿病,CAD,吸烟状态) 和国际前列腺症状评分 (IPSS) 的患者在基线和12个月.
- 多重回归分析以确定PAE结果的显著预测因素.
主要成果:
- 分析了100名患者的数据;平均年龄为65.8岁,基线IPSS为20.9.
- 高血压,糖尿病,CAD,吸烟状态,年龄和基线Qmax在PAE后12个月没有显著影响IPSS减少.
- 基线前列腺体积显著影响了IPSS减小,更大的前列腺 (≥80cc) 显示出更大的改善.
结论:
- 心血管并发症和吸烟史对12个月后的PAE症状评分结果没有显著影响.
- 在患有心血管并发症和没有心血管并发症的患者中,PAE的临床成功是可比的,前提是前列腺动脉是可访问的.
- 这些发现支持PAE作为BPH患者具有常见心血管风险因素的可行治疗选择.
相关概念视频
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
Endothelins (ETs) are potent vasoactive peptides critical in the human body's various physiological and pathological processes. One of the most promising therapeutic strategies for treating pulmonary arterial hypertension (PAH) involves counteracting the effects of these endothelins using a class of drugs known as endothelin receptor antagonists.
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...


