每天用4%的赫西丁 + 每天用赫西丁擦拭1周的洗是否可以有效地消除Candida auris殖民的殖民?
Umran Elbahr1, Amira Khairy2, Farouq Dayyab3
1Infectious Diseases Department, Bahrain Oncology Center, King Hamad University Hospital, AlMuharraq, Bahrain. drumran_08@hotmail.com.
概括
每天用4%的赫西丁洗,加上每天用4%的赫西丁擦拭剂 (DCHX) 清洁,在去殖民Candida auris携带者方面效果有限. 虽然DCHX并非完全无效,但它在患者的多个身体部位上被殖民时遇到了困难.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 黄是一种新兴的多药耐药性真菌病原体,造成了医疗保健方面的重大挑战.
- 有效的非殖民化策略对于控制C. auris在临床环境中的传播至关重要.
研究的目的:
- 为了评估Candida auris携带者的脱殖率,使用每日洗和擦拭方案使用4%的赫西丁 (DCHX) 一周.
主要方法:
- 一项观察性研究包括38名成年患者,他们的C. auris殖民被监测培养物证实.
- 患者每天洗并用4%的赫西丁 (DCHX) 擦拭七天.
- 解殖被定义为三个连续的负监测培养,分隔三天.
主要成果:
- 只有23.7% (9/38) 的患者在DCHX疗法后实现了脱殖.
- 不管同时服用抗生素或抗真菌疗法,脱殖率都相似.
- 两名脱殖的患者在30天内感染了C. auris,而10名未脱殖的患者则感染了C. auris.
结论:
- DCHX疗法对C. auris脱殖的有效性有限,特别是在多个身体部位殖民的患者中.
- 对C. auris更有效的脱殖协议进行进一步研究是有必要的.
- 这项研究强调了控制C. auris殖民的持续挑战.
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