相关实验视频

Updated: Jul 9, 2025

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma

Published on: August 31, 2022

声波刺肝细胞腺瘤:磁共振成像特征和与组织学相关性

Arnaud Ducatel¹, Hervé Trillaud², Edouard Reizine³

¹Department of Radiology, University Bordeaux Hospital, Hôpital Haut-Lévêque, F-33604, Pessac, France. arnaud.ducatel@chu-bordeaux.fr.

European radiology

|November 27, 2023

概括

声波刺肝细胞腺瘤 (shHCA) 是一种罕见的,高风险的亚型. 这项研究确定了MRI上的内液体填充腔作为shHCA的新潜在诊断发现,与组织学分析相关.

科学领域:

肝胆道成像检查肝胆道成像检查
胃肠道放射学胃肠道放射学
瘤成像 - - 癌症成像

背景情况:

声波刺肝细胞腺瘤 (shHCA) 是最近发现的肝细胞腺瘤的亚型.
shHCA与高出血风险有关,占所有HCA的10%以下.
此前没有确定shHCA的特定成像特征.

研究的目的:

评估磁共振成像 (MRI) 在识别shHCA中的实用性.
为了将MRI发现与shHCA的组织病理特征相关联.

主要方法:

对29名确诊shHCA (35种病变) 的患者的MRI扫描进行了回顾性分析.
通过免疫组织化学和分子/蛋白质组分析证实了shHCA诊断.
核磁共振成像结果与病理学检查的相关性.

主要成果:

在46%的shHCA病例中,在T2加权的MRI序列中发现了内流体填充的腔,T2加权的超强度和T1加权的低强度.
在病理学检查中,这些空洞与具有降解血液产品的真空相对应.
在71%的病例中,通过MRI检测出出血和/或亡,而病理检测出的是82%.

结论:

内流体填充的腔体代表了一种新的MRI发现,可能有助于诊断shHCA.
这项研究确立了MRI和shHCA的组织病理学之间的相关性.
这些发现表明这种罕见的肝细胞腺瘤亚型的特定成像模式.

关键词:

发生出血发生出血肝细胞腺瘤是一种肝细胞腺瘤.磁共振成像技术磁共振成像技术病理学病理学病理学索尼克刺蛋白质是一种刺蛋白质.

更多相关视频

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis

Published on: September 12, 2019

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

Published on: March 29, 2019

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...