通过二维斑点跟踪回声心脏学测量细分和全球纵向应变,用于严重的类风湿性额狭窄症
Samira Mehrabi-Pari1, Sepehr Nayebirad1, Akbar Shafiee1
1Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
BMC cardiovascular disorders
|November 28, 2023
概括
两维斑点跟踪回声心脏学检测了严重的风湿性心肌狭窄症患者的微妙左心室功能障碍. 在大多数基底和中心肌段中,细分菌株值明显较低,表明亚临床损伤.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管成像 - 心血管成像
背景情况:
- 风湿性额头狭窄症 (MS) 可以导致左心室 (LV) 功能障碍.
- 微妙的 LV 功能障碍可能存在,即使在重症多发性硬化中保留了喷射分数 (EF).
- 早期发现LV功能障碍对于管理MS患者至关重要.
研究的目的:
- 检测严重的风湿性额叶狭窄症 (MS) 患者中微妙的左心室 (LV) 功能障碍.
- 使用二维斑点跟踪回声心电图 (2D-STE) 来测量全球和细分纵向应变.
- 为了比较严重多发性硬化症患者和健康对照人群之间的LV菌株参数.
主要方法:
- 一项病例控制研究涉及65名患有严重风湿性多发性硬化和保存EF (≥50%) 的患者.
- 与31名健康对照人群进行比较.
- 在VIVID S60心声回声仪上使用2D-STE测量LV应变.
主要成果:
- 与对照组相比,MS患者的大多数基底和心肌中部细分部分的绝对纵向应变值显著较低 (P<0.05).
- 绝对全球纵向应变 (GLS) 在对照组 (-19.56) 中高于MS患者 (-18.25;P=0.006).
- 经过调整后,群体之间的GLS差异在统计学上并不显著 (P=0.110).
结论:
- 与健康对照组相比,患有重症类风湿性多发性硬化和保存EF的患者表现出较低绝对GLS的趋势.
- 在基底和心肌中部段中观察到细分LV菌株的显著减少.
- 需要进一步的研究来了解这种亚临床功能障碍的病理生理学和临床意义.
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