开始的秘密:通过Enterococcus和其他格拉姆阳性细菌的蛋白质酸化来调节酸甘合成的第一个承诺步骤

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Functional Complementation Analysis FCA: A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways
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Functional Complementation Analysis FCA: A Laboratory Exercise Designed and Implemented to Supplement the Teaching of Biochemical Pathways

Published on: June 24, 2016

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Malcolm E Winkler1, Merrin Joseph1, Ho-Ching T Tsui1

  • 1Department of Biology, Indiana University Bloomington, Bloomington, Indiana, USA.

Molecular microbiology
|November 28, 2023
PubMed
概括

在Enterococcus faecalis中,IreB蛋白酸化调节了MurAA水平,影响了类抗生素耐药性. 这一途径对于了解细菌对抗β-乳酸药物的防御机制至关重要.

关键词:
格拉姆阳性PASTA-域的Ser/Thr-蛋白激酶.在 IreB/ReoM 调控蛋白质.MurA-家族和MurZ-家族的同类物.的 ClpCP 蛋白酶的适配器.素耐药性机制的机制

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